The μ-opioid receptor-mediated Gi/o protein and β-arrestin2 signaling pathways both contribute to morphine-induced side effects
Jing Xia, Xiaoyan Li, Hongyu Zhu, Xiaohui Zhou, Jihua Chen, Qihong Li, Shupeng Li, Haichen Chu, Mingxin Dong, Haichen Chu, Mingxin Dong
Topics & Concepts
OpioidPharmacologyMorphineμ-opioid receptorChemistrySignal transductionAgonistReceptorPhosphorylationMedicineBiochemistryReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyCancer, Stress, Anesthesia, and Immune Response