<i>In Vitro</i> Antifungal Resistance of Candida auris Isolates from Bloodstream Infections, South Africa
Tsidiso G. Maphanga, Serisha D. Naicker, Stanford Kwenda, José F. Muñoz, Erika van Schalkwyk, Jeannette Wadula, Trusha Nana, Arshad Ismail, Jennifer Coetzee, Chetna Govind, Phillip Senzo Mtshali, Ruth Mpembe, Nelesh P. Govender
Abstract
. Most South African C. auris isolates were resistant to azoles, although resistance to polyenes and echinocandins was less common. We observed mutations in resistance genes even in phenotypically susceptible isolates.
Topics & Concepts
Candida aurisAnidulafunginFluconazoleEtestCaspofunginBiologyMicrobiologyMicafunginAmphotericin BPosaconazoleBroth microdilutionEchinocandinEchinocandinsMinimum inhibitory concentrationAntibioticsAntifungalAntifungal resistance and susceptibilityFungal Infections and StudiesPlant Pathogens and Fungal Diseases