Allosteric regulation of CAD modulates de novo pyrimidine synthesis during the cell cycle
Jong Shin, Hannan Mir, Maaz A. Khurram, Kenji M. Fujihara, Brian David Dynlacht, Timothy Cardozo, Richard Possemato
Topics & Concepts
Pyrimidine metabolismAllosteric regulationCell cycleBiologyBiochemistryCarbamoyl phosphate synthetaseUrea cycleAspartate carbamoyltransferaseDihydroorotate dehydrogenaseCell biologyEnzymeCellAmino acidPurineArginineBiochemical and Molecular ResearchRNA modifications and cancerErythrocyte Function and Pathophysiology