siRNA delivery to macrophages using aspherical, nanostructured microparticles as delivery system for pulmonary administration
Thorben Fischer, Thomas Tschernig, Franziska Drews, Kristina Brix, Carola Meier, Martín Simón, Ralf Kautenburger, Marc Schneider
Topics & Concepts
ChemistryOligonucleotideSmall interfering RNAProinflammatory cytokineIn vitroLiposomeBiophysicsDelivery systemDrug deliveryDrug carrierPharmacologyRNABiomedical engineeringNanotechnologyInflammationMaterials scienceImmunologyMedicineBiochemistryDNABiologyGeneRNA Interference and Gene DeliveryMembrane Separation TechnologiesInhalation and Respiratory Drug Delivery