HMGB1 promoted P-glycoprotein at the blood-brain barrier in MCAO rats via TLR4/NF-κB signaling pathway
Fei Wang, Shenglan Ji, Muxi Wang, Lu Liu, Qiaoling Li, Fuxia Jiang, Juan Cen, Bian‐Sheng Ji
Topics & Concepts
HMGB1Pyrrolidine dithiocarbamateBlood–brain barrierTLR4Signal transductionMicrovesselChemistryPharmacologyNF-κBEndotheliumReceptorMedicineCell biologyBiologyEndocrinologyInternal medicineBiochemistryCentral nervous systemAngiogenesisBarrier Structure and Function StudiesDrug Transport and Resistance MechanismsNeuroinflammation and Neurodegeneration Mechanisms