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KSHV-encoded ORF45 activates human NLRP1 inflammasome

Xing Yang, Jingfan Zhou, Chengrong Liu, Yafei Qu, Weili Wang, Maggie Z. X. Xiao, Fanxiu Zhu, Zhenshan Liu, Qiming Liang

2022Nature Immunology42 citationsDOI

Topics & Concepts

InflammasomePyrin domainNLRP1ProteasesSerine proteaseProteaseCell biologyOpen reading frameBiologyChemistryVirologyReceptorCaspasePeptide sequenceGeneticsBiochemistryGeneApoptosisEnzymeProgrammed cell deathInflammasome and immune disordersViral-associated cancers and disordersKawasaki Disease and Coronary Complications
KSHV-encoded ORF45 activates human NLRP1 inflammasome | Litcius