Hesperidin Methyl Chalcone reduces extracellular Aβ(25-35) peptide aggregation and fibrillation and also protects Neuro 2a cells from Aβ(25-35) induced neuronal dysfunction
Sakthivel Jafni, S. Sathya, Malaisamy Arunkumar, Chandramohan Kiruthiga, Mahalingam Jeyakumar, Easwaran Murugesh, Kasi Pandima Devi
Topics & Concepts
ChemistryNeuroprotectionHesperidinNeurotoxicityThioflavinAmyloid (mycology)Programmed cell deathPeptideOxidative stressPharmacologyBiochemistryBiophysicsApoptosisExtracellularCell biologyToxicityAlzheimer's diseaseBiologyInternal medicinePathologyDiseaseInorganic chemistryAlternative medicineMedicineOrganic chemistryAlzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery Methods