Litcius/Paper detail

Non-invasive electrophysiology in glaucoma, structure and function—a review

Khaldoon O. Al-Nosairy, Michael B. Hoffmann, Michael Bach

2021Eye18 citationsDOIOpen Access PDF

Abstract

Glaucoma, its early diagnosis, and monitoring of interventions remain an ongoing challenge. We here review developments in functional assessment and its relation to morphology, evaluating recent insights in electrophysiology in glaucoma and highlighting how glaucoma research and diagnostics benefit from combined approaches of OCT and electrophysiological investigations. After concise overviews of OCT and non-invasive electrophysiology in glaucoma, we evaluate commonalities and complementarities of OCT and electrophysiology for our understanding of glaucoma. As a specific topic, the dynamic range (floor effects) of the various techniques is discussed.

Topics & Concepts

GlaucomaElectrophysiologyMedicineOptometryOphthalmologyInternal medicineGlaucoma and retinal disordersRetinal Development and DisordersPhotoreceptor and optogenetics research