The role of mTORC1/TFEB axis mediated lysosomal biogenesis and autophagy impairment in fluoride neurotoxicity and the intervention effects of resveratrol
Huayang Tang, Haoqi Hou, Song Li, Zhiyuan Tian, Wenhui Liu, Tao Xia, Aiguo Wang
Topics & Concepts
TFEBAutophagyLysosomeNeurotoxicitymTORC1FluorideChemistryBiogenesisAutophagosomeCell biologyPharmacologyPI3K/AKT/mTOR pathwayBiologyBiochemistrySignal transductionToxicityInorganic chemistryApoptosisGeneEnzymeOrganic chemistryFluoride Effects and RemovalAdvanced Glycation End Products researchAutophagy in Disease and Therapy