Allicin mitigates hepatic injury following cyclophosphamide administration via activation of Nrf2/ARE pathways and through inhibition of inflammatory and apoptotic machinery
Dongsheng Sun, Chen Sun, Gongcai Qiu, Lei Yao, Jian Yu, Hassan Al Sberi, Manar S. Fouda, Mohamed S. Othman, Maha S. Lokman, Rami B. Kassab, Ahmed E. Abdel Moneim
Topics & Concepts
Glutathione peroxidaseGlutathioneAspartate transaminaseNitric oxide synthaseChemistryGlutathione reductaseDownregulation and upregulationSuperoxide dismutaseAlanine transaminaseNitric oxidePharmacologyAllicinMalondialdehydeBiochemistryAlkaline phosphataseBiologyEndocrinologyOxidative stressEnzymeGeneGarlic and Onion StudiesChemotherapy-induced organ toxicity mitigationNigella sativa pharmacological applications