Sequestered SQSTM1/p62 crosstalk with Keap1/NRF2 axis in hPDLCs promotes oxidative stress injury induced by periodontitis
Huiqing Gou, Xu Chen, Xiaoming Zhu, Lu Li, Liguang Hou, Yi Zhou, Yan Xu
Topics & Concepts
KEAP1Oxidative stressPeriodontitisInflammationPI3K/AKT/mTOR pathwayChemistrySOD2ImmunologyPathogenesisCell biologySignal transductionCancer researchMedicineBiologyBiochemistryInternal medicineSuperoxide dismutaseTranscription factorGeneOral microbiology and periodontitis researchAutophagy in Disease and TherapyHeme Oxygenase-1 and Carbon Monoxide