The development of advanced structural framework as multi-target-directed ligands for the treatment of Alzheimer’s disease
Zhipei Sang, Keren Wang, Jian Shi, Wenmin Liu, Xinfeng Cheng, Gaofeng Zhu, Yiling Wang, Yiyang Zhao, Zhanpin Qiao, Anguo Wu, Zhenghuai Tan
Topics & Concepts
ChemistryDonepezilPharmacologyOxidative stressNeuroprotectionGlutathioneIC50CurcuminBiochemistryIn vitroInternal medicineDementiaDiseaseMedicineEnzymeCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatmentsComputational Drug Discovery Methods