Autophagy inhibition by chloroquine and hydroxychloroquine could adversely affect acute kidney injury and other organ injury in critically ill patients with COVID-19
Charles L. Edelstein, Manjeri A. Venkatachalam, Zheng Dong
Topics & Concepts
ChloroquineHydroxychloroquineAutophagyAcute kidney injuryLysosomeMedicinePharmacologyCoronavirusImmunologyInternal medicineBiologyDiseaseCoronavirus disease 2019 (COVID-19)EnzymeBiochemistryMalariaInfectious disease (medical specialty)ApoptosisAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolismHeme Oxygenase-1 and Carbon Monoxide