Enhanced bioavailability and hepatoprotective effect of silymarin by preparing silymarin-loaded solid dispersion formulation using freeze-drying method
Dong Yu Lim, Minyeong Pang, Jaehyeok Lee, Jihoon Lee, Ji-Hyeon Jeon, Jin-Hyang Park, Min‐Koo Choi, Im‐Sook Song
Topics & Concepts
BioavailabilityChemistryPharmacologySilibininMilk ThistlePharmacokineticsHepatoprotectionGlucuronidationChromatographyMedicineBiochemistryGlutathioneIn vitroMicrosomeEnzymeSilymarin and Mushroom PoisoningDrug-Induced Hepatotoxicity and ProtectionPoisoning and overdose treatments