Litcius/Paper detail

Endometrial and Menstrual Blood Mesenchymal Stem/Stromal Cells: Biological Properties and Clinical Application

Mahmood Bozorgmehr, Shanti Gurung, Saeedeh Darzi, Shohreh Nikoo, Somaieh Kazemnejad, Amir‐Hassan Zarnani, Caroline E. Gargett

2020Frontiers in Cell and Developmental Biology251 citationsDOIOpen Access PDF

Abstract

population and enhances their potency, suggesting potential for cell-therapies and regenerative medicine. However, standardization of MenSC isolation protocols and culture conditions are major issues requiring further research to maximize their potential for clinical application. Future research will also address crucial safety aspects of eMSC and MenSC to ensure these protocols produce cell products free from tumorigenicity and toxicity. Although a wealth of data on the biological properties of eMSC and MenSC has recently been published, it will be important to address their mechanism of action in preclinical models of human disease.

Topics & Concepts

Mesenchymal stem cellStromal cellStem cellPopulationBiologyClonogenic assayImmunologyCD34ImmunophenotypingCancer researchMedicineCell biologyCellFlow cytometryGeneticsEnvironmental healthMesenchymal stem cell researchReproductive System and PregnancyCongenital Diaphragmatic Hernia Studies