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Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models

Xinjie Guan, Zhi-qiang Deng, Jia Liu, Cheng-Fu Su, Benjamin Chun‐Kit Tong, Zhou Zhu, Sravan Gopalkrishnashetty Sreenivasmurthy, Yuxuan Kan, Kejia Lu, Carol Pui‐Kei Chu, Rongbiao Pi, King‐Ho Cheung, Ashok Iyaswamy, Ju‐Xian Song, Min Li

2024Acta Pharmacologica Sinica36 citationsDOIOpen Access PDF

Topics & Concepts

TFEBAutophagyTFE3Basic helix-loop-helix leucine zipper transcription factorsTranscription factorBiologyCell biologyPI3K/AKT/mTOR pathwayCancer researchNeuroscienceEnhancerSignal transductionBiochemistryDNA-binding proteinApoptosisGeneAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolismParkinson's Disease Mechanisms and Treatments
Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models | Litcius