Enhancing Diagnostics in Orthopedic Infections
Eibhlin Higgins, Gina A. Suh, Aaron J. Tande
Abstract
Accurate diagnosis of orthopedic infection is crucial in guiding both antimicrobial therapy and surgical management in order to optimize patient outcomes. A variety of microbiological and nonmicrobiological methods are used to establish the presence of a musculoskeletal infection. In this minireview, we examine traditional culture-based and newer molecular methodologies for pathogen detection, as well as systemic and localized assays to assess host response to maximize diagnostic yield.
Topics & Concepts
Orthopedic surgeryIntensive care medicineMedicinePathogenAntimicrobialBiologyImmunologySurgeryMicrobiologyOrthopedic Infections and TreatmentsInfectious Diseases and TuberculosisBacterial Identification and Susceptibility Testing