Human microglia maturation is underpinned by specific gene regulatory networks
Claudia Z. Han, Rick Z. Li, Emily A. Hansen, Samantha Trescott, Bethany Fixsen, Celina T. Nguyen, Cristina Mora, Nathanael J. Spann, Hunter Bennett, Olivier Poirion, Justin Buchanan, Anna S. Warden, Bing Xia, Johannes C. M. Schlachetzki, Martina P. Pasillas, Sebastian Preißl, Allen Wang, Carolyn O’Connor, Shreya Shriram, Roy Kim, Danielle Schafer, Gabriela Ramírez, Jean F. Challacombe, Samuel A. Anavim, Avalon Johnson, Mihir Gupta, Ian A. Glass, Michael L. Levy, Sharona Ben Haim, David Gonda, Louise C. Laurent, Jennifer F. Hughes, David C. Page, Mathew Blurton‐Jones, Christopher K. Glass, Nicole G. Coufal
Topics & Concepts
MicrogliaBiologyEnhancerInduced pluripotent stem cellEpigeneticsPhenotypeTranscriptomeTranscription factorGeneHuman brainGene regulatory networkNeuroscienceFetusEmbryonic stem cellCell biologyComputational biologyImmunologyGeneticsGene expressionInflammationPregnancyNeuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomicsMicroRNA in disease regulation