Stereoselective synthesis of 1,3- and 1,4-dicarbonyl-alkenes from cyclopropenes in a catalytic zinc system
Jia‐Bin Han, Yu Liu, Xiaoyan Yang, Xuheng Zhang, Yuanhao Zhu, Min Zhao, Ge‐Fei Hao, Yaojia Jiang
Abstract
This work describes a dual catalytic system for selective synthesis of α-allyl-1,3-ketoaldehydes and α-vinyl-1,4-ketoaldehydes through cascade reactions of hydroxyl substituted aromatic enaminones with cyclopropenes under zinc promoted conditions.
Topics & Concepts
ChemistryZincCatalysisStereoselectivityCombinatorial chemistryCascadeOrganic chemistryChromatographyCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsCatalytic Alkyne Reactions