A visible-light-promoted metal-free approach for N–H insertions by using donor/donor diazo precursors
Yu Zhang, Qiannan Li, Ping Wang, Jinxin Wang, Jingchuan Lin, Dingding Xia, Er‐Jun Hao, Xin Luan, Shoubhik Das, Weidong Zhang
Abstract
A metal-free and catalyst-free strategy is reported to achieve N–H insertions by coupling N -tosylhydrazones with diverse amines including aminopyridines, anilines, aliphatic amines, and other nucleophiles such as imidazoles and indoles.
Topics & Concepts
DiazoChemistryMetalCombinatorial chemistryVisible spectrumPhotochemistryStereochemistryOrganic chemistryMaterials scienceOptoelectronicsCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsSynthesis and Catalytic Reactions