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Gasdermin D pore structure reveals preferential release of mature interleukin-1

Shiyu Xia, Zhibin Zhang, Venkat Giri Magupalli, Juan Lorenzo Pablo, Ying Dong, Setu M. Vora, Longfei Wang, Tian‐Min Fu, Matthew P. Jacobson, Anna Greka, Judy Lieberman, Jianbin Ruan, Hao Wu

2021Nature612 citationsDOIOpen Access PDF

Topics & Concepts

BiophysicsChemistryPyroptosisIntracellularInflammasomeOrganelleCell biologyBiochemistryBiologyReceptorInflammasome and immune disordersStreptococcal Infections and TreatmentsAutoimmune and Inflammatory Disorders Research
Gasdermin D pore structure reveals preferential release of mature interleukin-1 | Litcius