Epigenetically-regulated miR-30a/c-5p directly target TWF1 and hamper ccRCC cell aggressiveness
Gonçalo Outeiro-Pinho, Daniela Barros‐Silva, Filipa Moreira‐Silva, João Lobo, Isa Carneiro, António Morais, Eduarda P. Martins, Céline S. Gonçalves, Bruno M. Costa, Margareta P. Correia, Rui Henrique, Cármen Jerónimo
Topics & Concepts
DNA methylationBiologyClear cell renal cell carcinomaCancer researchEpithelial–mesenchymal transitionmicroRNAEpigeneticsDownregulation and upregulationMethylationCpG siteMolecular biologyGene expressionGenePathologyMedicineGeneticsRenal cell carcinomaEpigenetics and DNA MethylationRenal and related cancersRenal cell carcinoma treatment