Medial PFC AMPA receptor and BDNF signaling are required for the rapid and sustained antidepressant-like effects of 5-HT1A receptor stimulation
Kenichi Fukumoto, Manoela V. Fogaça, Rong-Jian Liu, Catharine H. Duman, Xiaoyuan Li, Shigeyuki Chaki, Ronald S. Duman
Topics & Concepts
AMPA receptor5-HT1A receptorAntidepressantAgonistBrain-derived neurotrophic factorReceptor antagonistTropomyosin receptor kinase BNeuroscienceStimulationChemistryPrefrontal cortexEndocrinologyNeurotrophic factorsInternal medicineReceptorNMDA receptorPharmacologyPsychology5-HT receptorAntagonistHippocampusBiologySerotoninMedicineCognitionTreatment of Major DepressionNeurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research