Preventing necroptosis by scavenging ROS production alleviates heat stress-induced intestinal injury
Li Li, Hongping Tan, Zhimin Zou, Jian Gong, Junjie Zhou, Na Peng, Lei Su, Marc Maegele, Daozhang Cai, Zhengtao Gu
Abstract
. These findings provide a clear target for future mechanism-based therapeutic strategies for patients diagnosed with heat stroke.
Topics & Concepts
Programmed cell deathNecroptosisReactive oxygen speciesOxidative stressApoptosisBiologyFlow cytometryViability assayMolecular biologyCell biologyChemistryBiochemistryClimate Change and Health ImpactsThermoregulation and physiological responsesVitamin C and Antioxidants Research