3,4-benzo[a]pyrene aggravates myocardial infarction injury by activating NLRP3-related pyroptosis through PINK1/Parkin-mitophagy-mPTP opening axis
Bo-Sen Wu, Huaqiang Xiang, Yongwei Yu, Shuai Liu, Dong-yan Song, Chang Wu, Zhi-hui Lin, Chen-xi Zhu, Yangjing Xue, Kangting Ji
Topics & Concepts
PINK1ParkinMitophagyMPTPPyroptosisPharmacologyAryl hydrocarbon receptorMedicineChemistryProgrammed cell deathInternal medicineApoptosisDiseaseBiochemistryAutophagyParkinson's diseaseTranscription factorGeneAutophagy in Disease and TherapyAir Quality and Health ImpactsHeme Oxygenase-1 and Carbon Monoxide