Litcius/Paper detail

A systematic review: Sinomenine

Shan Jiang, Shuang Li, Si-yuan Pang, Mei Liu, Huifeng Sun, Ning Zhang, Jianxin Liu

2024Heliyon17 citationsDOIOpen Access PDF

Abstract

, has been used as an anti-inflammatory drug in China for over 30 years. With the continuous increase in research on the pharmacological mechanism of SIN, it has been found that, in addition to the typical rheumatoid arthritis (RA) treatment, SIN can be used as a potentially effective therapeutic drug for anti-tumour, anti-renal, and anti-nervous system diseases. By reviewing a large amount of literature and conducting a summary analysis of the literature pertaining to the pharmacological mechanism of SIN, we completed a review that focused on SIN, found that the current research is insufficient, and offered an outlook for future SIN development. We hope that this review will increase the public understanding of the pharmacological mechanisms of SIN, discover SIN research trial shortcomings, and promote the effective treatment of immune diseases, inflammation, and other related diseases.

Topics & Concepts

SinomenineMechanism (biology)MedicineRheumatoid arthritisIntensive care medicineTraditional Chinese medicineAlternative medicineTraditional medicineDrugPharmacologyImmunologyPathologyPhilosophyEpistemologyBerberine and alkaloids researchSynthesis and bioactivity of alkaloidsDrug Transport and Resistance Mechanisms