Palladium-catalyzed intramolecular diastereoselective dearomatization reaction of indoles with <i>N</i>-tosylhydrazones
Shao-Bo Duan, Hong‐Yu Zhang, Bo‐Ya Hao, Jiquan Zhao, Yaping Han, Yuecheng Zhang, Yong‐Min Liang
Abstract
A novel, highly diastereoselective palladium-catalyzed dearomative reaction of N -halobenzoyl o -haloaniline derivatives has been developed using functionalized N -tosylhydrazones as the coupling partners.
Topics & Concepts
ChemistryPalladiumIntramolecular forceCatalysisCombinatorial chemistryCoupling reactionOrganic chemistryCatalytic C–H Functionalization MethodsCyclopropane Reaction MechanismsSynthesis and Catalytic Reactions