TGF β1 promotes the polarization of M2-type macrophages and activates PI3K/mTOR signaling pathway by inhibiting ISG20 to sensitize ovarian cancer to cisplatin
Jianfa Wu, Lingli Jiang, Sihong Wang, Lei Peng, Rong Zhang, Zhou Liu
Topics & Concepts
PI3K/AKT/mTOR pathwayCancer researchCisplatinOvarian cancerSignal transductionCell biologyBiologyMedicineCancerInternal medicineChemotherapyImmune cells in cancerEpigenetics and DNA MethylationOvarian cancer diagnosis and treatment