Litcius/Paper detail

The substrate repertoire of γ-secretase/presenilin

Gökhan Güner, Stefan F. Lichtenthaler

2020Seminars in Cell and Developmental Biology203 citationsDOIOpen Access PDF

Topics & Concepts

PresenilinEctodomainBiologyCleavage (geology)Amyloid precursor protein secretaseAlpha secretaseCell biologyProteaseAmyloid precursor proteinTransmembrane proteinProtein subunitTransmembrane domainBiochemistryGamma secretaseSignal transductionEnzymeAlzheimer's diseaseMembraneReceptorGenePathologyFracture (geology)MedicinePaleontologyDiseaseAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsMedicinal Plants and Neuroprotection