The tumor phototherapeutic application of nanoparticles constructed by the relationship between PTT/PDT efficiency and 2,6- and 3,5-substituted BODIPY derivatives
Juanjuan Yin, Jiang Xu, Guomin Sui, Yingying Du, Enyun Xing, Ruijie Shi, Cheng‐Zhi Gu, Wen Xiaona, Yaqing Feng, Zhongqiang Shan, Shuxian Meng
Abstract
In this study, we designed and synthesized nine novel BODIPY near-infrared dyes, and discussed the relationship between their structures and photothermal/photodynamic effects. The prepared nanoparticles showed excellent biocompatibility and anti-tumor efficiency.
Topics & Concepts
BODIPYNanoparticleMaterials sciencePhotodynamic therapyNanotechnologyPhotochemistryChemical engineeringCombinatorial chemistryChemistryOrganic chemistryFluorescenceOpticsEngineeringPhysicsNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsPhotodynamic Therapy Research Studies