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Autoimmune Hepatitis Triggered by COVID-19 Vaccine: The First Case From Inactivated Vaccine

Krittaya Mekritthikrai, Peera Jaru-Ampornpan, Piyawat Komolmit, Kessarin Thanapirom

2022ACG Case Reports Journal19 citationsDOIOpen Access PDF

Abstract

We report a case of a 52-year-old woman without previous underlying liver disease, presenting with progressive jaundice and diagnosed with autoimmune hepatitis after 2 doses of an inactivated coronavirus disease 2019 (CoronaVac) vaccine. All serology and histology were compatible with autoimmune hepatitis. Symptoms were improved and liver function tests were normalized after treatment with steroids and azathioprine.

Topics & Concepts

MedicineAutoimmune hepatitisAzathioprineSerologyJaundiceImmunologyHepatitis A vaccineHepatitisVirologyDiseaseHepatitis AGastroenterologyInternal medicineAntibodyLiver Diseases and ImmunitySARS-CoV-2 and COVID-19 ResearchHepatitis Viruses Studies and Epidemiology