Design, synthesis, in vitro and in silico studies of some novel thiazole-dihydrofuran derivatives as aromatase inhibitors
Derya Osmani̇ye, Şennur Görgülü, Begüm Nurpelin Sağlık, Serkan Levent, Yusuf Özkay, Zafer Asım Kaplancıklı
Topics & Concepts
AromataseChemistryThiazoleMTT assayIn vitroCell cultureFlow cytometryIn silicoStereochemistryApoptosisBiochemistryMolecular biologyCancerBreast cancerInternal medicineBiologyGeneticsGeneMedicineEstrogen and related hormone effectsBioactive Compounds and Antitumor AgentsFerrocene Chemistry and Applications