Litcius/Paper detail

Activation of the GLP-1 receptor by a non-peptidic agonist

Peishen Zhao, Yi-Lynn Liang, Matthew J. Belousoff, Giuseppe Deganutti, Madeleine M. Fletcher, Francis S. Willard, Michael G. Bell, Michael E. Christe, Kyle W. Sloop, Asuka Inoue, Tin T. Truong, Lachlan Clydesdale, Sebastian G. B. Furness, Arthur Christopoulos, Ming-Wei Wang, Laurence J. Miller, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton, Denise Wootten

2020Nature168 citationsDOIOpen Access PDF

Topics & Concepts

Transmembrane domainTransmembrane proteinReceptorAgonistBiophysicsG protein-coupled receptorHelix (gastropod)PeptideExtracellularChemistryGlucagon-like peptide 1 receptorCell biologyBiochemistryBiologyEcologySnailReceptor Mechanisms and SignalingDiabetes Treatment and ManagementNeuropeptides and Animal Physiology