<scp>l</scp>-Asparagine–EDTA–amide silica-coated MNPs: a highly efficient and nano-ordered multifunctional core–shell organocatalyst for green synthesis of 3,4-dihydropyrimidin-2(1<i>H</i>)-one compounds
Negin Rostami, Mohammad G. Dekamin, Ehsan Valiey, Hamidreza Fanimoghadam
Abstract
-APTS-EDTA-asparagine MNPs, as a catalyst having excellent thermal and magnetic stability, specific morphology and acidic sites with appropriate geometry, can activate the Biginelli reaction components. Moreover, the environmental-friendliness and nontoxic nature of the catalyst, cost effectiveness, low catalyst loading, easy separation of the catalyst from the reaction mixture and short reaction time are some of the remarkable advantages of this green protocol.
Topics & Concepts
AsparagineChemistryAmideNanomaterialsLinkerNanoparticleSolventPolymer chemistryCombinatorial chemistryChemical engineeringNuclear chemistryOrganic chemistryNanotechnologyMaterials scienceEngineeringOperating systemComputer scienceEnzymeMulticomponent Synthesis of HeterocyclesSynthesis and biological activityMicrowave-Assisted Synthesis and Applications