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Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome

Bas J. H. M. Rosier, Albert J. Markvoort, Berta Gumí‐Audenis, Job A. L. Roodhuizen, Anniek den Hamer, Luc Brunsveld, Tom F. A. de Greef

2020Nature Catalysis95 citationsDOIOpen Access PDF

Topics & Concepts

DNA origamiApoptosomeCell biologySignal transducing adaptor proteinInnate immune systemBiologySignallingCaspaseDNASignal transductionProgrammed cell deathBiochemistryApoptosisReceptorRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesImmunotherapy and Immune Responses
Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome | Litcius