Polyoxometalate–covalent organic framework hybrid materials for pH-responsive photothermal tumor therapy
Wenxin Wang, Yuting Song, Jiayi Chen, Yanyan Yang, Jiawei Wang, Yan Song, Jiatong Ni, Minglu Tang, Junge Zhao, Yuan Sun, Tiedong Sun, Jinsong Peng
Abstract
a one-pot method. The resultant HPB@COF platform exhibited desirable biocompatibility, pH-responsive release properties and high tumor inhibition efficiency, which can be used for PTT to effectively inhibit tumor growth. Our work provides a valuable paradigm for the fabrication of safer and effective HPB@COF NPs for future pH-responsive photothermal therapy.
Topics & Concepts
BiocompatibilityPhotothermal therapyMaterials scienceNanotechnologyCovalent bondThermal stabilityPolyoxometalateFabricationChemistryCatalysisOrganic chemistryMedicineMetallurgyAlternative medicinePathologyCovalent Organic Framework ApplicationsMetal-Organic Frameworks: Synthesis and ApplicationsAdvanced Photocatalysis Techniques