Rationally designed Ru(<scp>ii</scp>)-metallacycle chemo-phototheranostic that emits beyond 1000 nm
Chonglu Li, Yuling Xu, Le Tu, Minhyeok Choi, Yifan Fan, Xiaoqiang Chen, Jonathan L. Sessler, Jong Seung Kim, Yao Sun
Abstract
studies involving the use of a nanoparticle formulation served to confirm that Ru1100 allows for high-performance NIR-II fluorescence imaging-guided precise chemo-phototherapy in the case of A549 tumour mouse xenografts with no obvious side effects. This work thus provides a paradigm for the development of long-wavelength emissive supramolecular theranostic agents based on ruthenium.
Topics & Concepts
MetallacycleIn vivoPenetration (warfare)WavelengthChemistryNanotechnologyMaterials sciencePhysicsOptoelectronicsOpticsBiologyX-ray crystallographyDiffractionBiotechnologyOperations researchEngineeringNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsSupramolecular Chemistry and Complexes