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Type B lactic acidosis: a rare oncological emergency

Qiuying Selina Liu, Farzana Harji, Anna Jones, Amy Tarnower

2020BMJ Case Reports13 citationsDOIOpen Access PDF

Abstract

Type B lactic acidosis is a rare metabolic complication of malignancy, more commonly in haematological malignancies. Due to the lack of formal prospective trials, treatment of lactic acidosis associated with malignancy is based on case reports. Given the poor prognosis, early recognition of type B lactic acidosis and prompt treatment are crucial. We report the first case of type B lactic acidosis in metastatic melanoma, followed by a brief literature review on the proposed pathophysiology and treatment.

Topics & Concepts

Lactic acidosisMedicineMalignancyAcidosisComplicationMetabolic acidosisIntensive care medicinePathophysiologyInternal medicineCancer, Hypoxia, and MetabolismAmino Acid Enzymes and MetabolismMedical Imaging Techniques and Applications
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