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Methadone-Involved Overdose Deaths in the US Before and After Federal Policy Changes Expanding Take-Home Methadone Doses From Opioid Treatment Programs

Christopher M. Jones, Wilson M. Compton, Beth Han, Grant Baldwin, Nora D. Volkow

2022JAMA Psychiatry81 citationsDOIOpen Access PDF

Abstract

Methadone-Involved Overdose Deaths in the US Before andAfterFederalPolicyChangesExpandingTake-Home Methadone Doses From Opioid Treatment Programs On March 16, 2020, to facilitate access to methadone treatment from opioid treatment programs (OTPs) during the COVID-19 pandemic, the Substance Abuse and Mental Health Services Administration allowed states to request blanket exceptions to provide up to 28 and 14 days of take-home methadone for stable and less stable patients, respectively; this signaled a shift in practice because most patients historically receive methadone daily from OTPs. 1

Topics & Concepts

MethadoneMedicineOpioidOpioid overdoseOpioid use disorderMethadone maintenanceSubstance abuseAnesthesiaEmergency medicinePsychiatry(+)-NaloxoneInternal medicineReceptorOpioid Use Disorder TreatmentCardiac Arrest and ResuscitationPain Management and Opioid Use