Skeletal muscle heme oxygenase-1 activity regulates aerobic capacity
Rodrigo Wagner Alves de Souza, David Gallo, Ghee Rye Lee, Eri Katsuyama, Alexa Schaufler, Janick Weber, Eva Csizmadia, George C. Tsokos, Lauren G. Koch, Steven L. Britton, Ulrik Wisløff, Patrı́cia C. Brum, Leo E. Otterbein
Abstract
controls. Collectively, these data define a role for heme and HO-1 as central regulators in the physiologic response of skeletal muscle to exercise.
Topics & Concepts
Skeletal muscleHeme oxygenaseHemeHMOX1EndocrinologyInternal medicineMuscle atrophyBiologyAtrophyChemistryBiochemistryMedicineEnzymeHeme Oxygenase-1 and Carbon MonoxideHigh Altitude and HypoxiaCardiac Arrest and Resuscitation