Effects of gastrodin against carbon tetrachloride induced kidney inflammation and fibrosis in mice associated with the AMPK/Nrf2/HMGB1 pathway
Jie-Qiong Ma, Yun-Zhi Sun, Qing-Lei Ming, Zhi-Kai Tian, Yujia Zhang, Chan-Min Liu
Abstract
Gastrodin (GAS), the main phenolic glycoside extracted from <italic>Gastrodia elata</italic> Blume, exhibits potential renoprotective properties.
Topics & Concepts
GastrodinGastrodia elataHMGB1Carbon tetrachlorideInflammationChemistryGlycosidePharmacologyFibrosisKidneyAMPKCYP2E1MedicineBiochemistryInternal medicineCytochrome P450PathologyStereochemistryChromatographyOrganic chemistryMetabolismProtein kinase AEnzymeTraditional Chinese medicineAlternative medicineBiological and pharmacological studies of plantsDietary Effects on HealthGenomics, phytochemicals, and oxidative stress