A bacterial biosynthetic pathway for methylated furan fatty acids
Rachelle A. S. Lemke, Stephanie M. Olson, Kaitlin Morse, Steven D. Karlen, Alan Higbee, Emily T. Beebe, John Ralph, Joshua J. Coon, Brian G. Fox, Timothy J. Donohue
Abstract
also contains a SAM-dependent methylase, FufM, that produces 9D5-FuFA from 9M5-FuFA. These results uncover the biochemical sequence of intermediates in a bacterial pathway for 9M5-FuFA and 9D5-FuFA biosynthesis and suggest the existence of homologs of the enzymes identified here that could function in FuFA biosynthesis in other organisms.
Topics & Concepts
FuranChemistryBiochemistryBiosynthesisOrganic chemistryGenePotato Plant ResearchLipid metabolism and biosynthesisMicrobial Metabolic Engineering and Bioproduction