Reverse pharmacology of Nimbin-N2 attenuates alcoholic liver injury and promotes the hepatoprotective dual role of improving lipid metabolism and downregulating the levels of inflammatory cytokines in zebrafish larval model
Gokul Sudhakaran, Pandurangan Prathap, Ajay Guru, B. Haridevamuthu, Raghul Murugan, Bader O. Almutairi, Mikhlid H. Almutairi, Annie Juliet, Pushparathinam Gopinath, Jesu Arockiaraj
Topics & Concepts
Oxidative stressLiver injuryZebrafishLipid peroxidationDownregulation and upregulationPharmacologyInflammationAlcoholic liver diseaseLipid metabolismProinflammatory cytokineHepatocyteHepatoprotectionChemistryBiologyImmunologyBiochemistryGlutathioneMedicineInternal medicineIn vitroEnzymeGeneCirrhosisAlcohol Consumption and Health EffectsLiver Disease Diagnosis and TreatmentEicosanoids and Hypertension Pharmacology