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Multiple substrate recognition by yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase through phosphate clamping

M.A. Marquez-Monino, Raquel Ortega-García, Megan L. Shipton, Elsa Franco-Echevarría, Andrew M. Riley, J. Sanz‐Aparicio, Barry V. L. Potter, Beatriz González

2021Science Advances27 citationsDOIOpen Access PDF

Abstract

DDP1 and orthologs as potential targets to address fungal infections and other health concerns.

Topics & Concepts

PolyphosphateBiochemistryYeastInorganic pyrophosphataseEnzymeSubstrate (aquarium)PhosphateSaccharomyces cerevisiaeBiologyPhosphorylationPyrophosphataseChemistryPyrophosphateEcologyCellular transport and secretionAdenosine and Purinergic SignalingCoagulation, Bradykinin, Polyphosphates, and Angioedema
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