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Neddylation-dependent LSD1 destabilization inhibits the stemness and chemoresistance of gastric cancer

Yan-Jia Guo, Jing‐Ru Pang, Yu Zhang, Zhongrui Li, Xiaolin Zi, Hong‐Min Liu, Ning Wang, Lijuan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng‐Yun Jin, Ying Liu, Yi‐Chao Zheng

2023International Journal of Biological Macromolecules10 citationsDOIOpen Access PDF

Topics & Concepts

NeddylationNEDD8DemethylaseUbiquitinCancerCancer cellChemistryCancer researchLysineDeubiquitinating enzymeCancer stem cellHistoneCell biologyBiologyBiochemistryStem cellAmino acidUbiquitin ligaseGeneticsGeneEpigenetics and DNA MethylationHistone Deacetylase Inhibitors ResearchCancer-related gene regulation
Neddylation-dependent LSD1 destabilization inhibits the stemness and chemoresistance of gastric cancer | Litcius