Isatin-hydrazide conjugates as potent α-amylase and α-glucosidase inhibitors: Synthesis, structure and in vitro evaluations
Inzamam Abbasi, Humaira Nadeem, Adil Saeed, Hafiz Aamir Ali Kharl, Muhammad Nawaz Tahir, Muhammad Moazzam Naseer
Topics & Concepts
AcarboseIsatinChemistryIC50HydrazideIn vitroEnzymeAmylaseConjugateBiochemistryPostprandialLead compoundCombinatorial chemistryDiabetes mellitusOrganic chemistryEndocrinologyMedicineMathematical analysisMathematicsEnzyme Production and CharacterizationNatural Antidiabetic Agents StudiesProtein Kinase Regulation and GTPase Signaling