Assessing the drug resistance profiles of oral probiotic lozenges
Yi Wang, Jingya Dong, Junyi Wang, Wei Chi, Wei Zhou, Qiwen Tian, Yue Hong, Xuan Zhou, Hailv Ye, Xuechen Tian, Rongdang Hu, Aloysius Wong
Abstract
BACKGROUND: Probiotic lozenges have been developed to harvest the benefits of probiotics for oral health, but their long-term consumption may encourage the transfer of resistance genes from probiotics to commensals, and eventually to disease-causing bacteria. AIM: . RESULTS: was also present. We found no conjugal transfer of streptomycin resistance genes in our co-incubation experiments. CONCLUSION: Our study represents the first antibiotic resistance profiling of probiotics from oral lozenges, thus highlighting the health risk especially in the prevailing threat of drug resistance globally.
Topics & Concepts
LozengeProbioticDrugMedicineDrug resistanceDentistryPharmacologyMicrobiologyBiologyBacteriaGeographyGeneticsArchaeologyProbiotics and Fermented FoodsMicrobial Metabolites in Food BiotechnologyDigestive system and related health