Induction of Unique STAT Heterodimers by IL-21 Provokes IL-1RI Expression on CD8<sup>+</sup>T Cells, Resulting in Enhanced IL-1β Dependent Effector Function
Dong Hyun Kim, Hee Young Kim, Won‐Woo Lee
Abstract
T cells by IL-21 may be beneficial to the protective immune response against viral infections and is therefore important to consider for vaccine design.
Topics & Concepts
Cytotoxic T cellGranzyme BCell biologyIL-2 receptorCD8EffectorBiologyPriming (agriculture)Interleukin 21CytokineImmune systemChemistryT cellImmunologyIn vitroBiochemistryGerminationBotanyImmune Cell Function and InteractionT-cell and B-cell ImmunologyImmune Response and Inflammation