αSMA+ fibroblasts suppress Lgr5+ cancer stem cells and restrain colorectal cancer progression
Kathleen M. McAndrews, Karina Vázquez-Arreguín, Changsoo Kwak, Hikaru Sugimoto, Xiaofeng Zheng, Bingrui Li, Michelle L. Kirtley, Valerie S. LeBleu, Raghu Kalluri
Topics & Concepts
LGR5Cancer-Associated FibroblastsBiologyTumor microenvironmentCancer stem cellTumor progressionCancer researchStromal cellParacrine signallingStem cellColorectal cancerCancerMetastasisTumor initiationCancer cellImmunologyCell biologyGeneticsTumor cellsReceptorBiochemistryCancer Cells and MetastasisImmune cells in cancerEpigenetics and DNA Methylation