Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth
Le Sun, Yu Yan, Heng Lu, Jianlong Li, Zhiyuan Wang, Kun Wang, Lin Wang, Yunxia Li, Hong Jiang, Yaoyang Zhang
Topics & Concepts
STAT3PI3K/AKT/mTOR pathwayCancer researchIn vivoSirolimusMechanistic target of rapamycinTranscription factorTranscription (linguistics)Cell growthBiologySignal transductionGeneCell biologyGeneticsLinguisticsBiochemistryPhilosophyPI3K/AKT/mTOR signaling in cancerCytokine Signaling Pathways and InteractionsBioactive Compounds and Antitumor Agents